Claudius Galen (130-202 AD) discovered the relationship between the nervous system of the spine and healing. He wrote, "Look to the nervous system as the key to maximum health." He earned the title 'Prince of Physicians' when he relieved the paralysis of the right hand of Eudemas (a prominent Roman scholar) by careful manipulation of his neck.
Herodotus gained fame curing diseases by correcting spinal abnormalities through therapeutic exercises. Aristotle was critical of Herodotus' tonic-free approach because, "he made old men young and thus prolonged their lives too greatly."
Socrates (469-399 BC) advised, "If you would seek health, look first to the spine."
Hippocrates, the Father of Medicine (460-370 BC), described manipulative procedures in his monumental work known as the Corpus Hippocrateum. He wrote, "Get knowledge of the spine, for this is the requisite for many diseases."